abstract：OBJECTIVE:To determine whether diurnal variation occurs in the onset of stroke. DESIGN:Community based study over four years. SETTING:Oxfordshire, United Kingdom. SUBJECTS:105,000 people, of whom 675 had a first ever stroke. 545 had a cerebral infarction, 66 had primary intracerebral haemorrhage, 33 had subarachnoid...

journal_title：BMJ (Clinical research ed.)

authors： Wroe SJ,Sandercock P,Bamford J,Dennis M,Slattery J,Warlow C

更新日期：1992-01-18 00:00:00

abstract：OBJECTIVE:To study the impact of skin surgery in general practice on the workload of a pathology laboratory and to identify what further training might be helpful. DESIGN:Analysis of skin biopsy specimens from general practitioners before and after their new contract to determine numbers of specimens, changes in diagn...

journal_title：BMJ (Clinical research ed.)

authors： Cox NH,Wagstaff R,Popple AW

更新日期：1992-01-11 00:00:00

abstract：OBJECTIVE:To study the circumstances of dog bites and identify risk factors. DESIGN:Postal questionnaire survey and case note review of victims of dog bites referred between 1982 and 1989. SETTING:One referral based regional plastic surgery unit. PATIENTS:146 consecutive patients referred for primary treatment of do...

journal_title：BMJ (Clinical research ed.)

authors： Shewell PC,Nancarrow JD

更新日期：1991-12-14 00:00:00

abstract：OBJECTIVE:To describe and quantify patterns of injury from antipersonnel mines in terms of distribution of injury, drain on surgical resources, and residual disability. DESIGN:Retrospective analysis. SETTING:Two hospitals for patients injured in war. SUBJECTS:757 patients with injuries from antipersonnel mines. MAI...

journal_title：BMJ (Clinical research ed.)

authors： Coupland RM,Korver A

更新日期：1991-12-14 00:00:00

abstract：OBJECTIVES:To measure, in a service setting, the effect of magnetic resonance imaging on diagnosis, diagnostic certainty, and patient management in the neurosciences; to measure the cost per patient scanned; to estimate the marginal cost of imaging and compare this with its diagnostic impact; to measure changes in pati...

journal_title：BMJ (Clinical research ed.)

authors： Szczepura AK,Fletcher J,Fitz-Patrick JD

更新日期：1991-12-07 00:00:00

abstract：OBJECTIVE:To determine if any excess of childhood leukaemia was associated with the large and increasing numbers of national military servicemen in 1949 and 1950, particularly in rural districts. This would be a further test of the hypothesis that childhood leukaemia can originate in an infection, the transmission of w...

journal_title：BMJ (Clinical research ed.)

authors： Kinlen LJ,Hudson C

更新日期：1991-11-30 00:00:00

abstract：OBJECTIVES:To develop a systematic method for both summative and formative audit of practice audits, and to use the method to review Oxfordshire practice audits and to plan improvement. DESIGN:Development of a coding system for the audit cycle subsequently used prospectively to assess audits reported to medical audit ...

journal_title：BMJ (Clinical research ed.)

authors： Derry J,Lawrence M,Griew K,Anderson J,Humphreys J,Pandher KS

更新日期：1991-11-16 00:00:00

abstract：OBJECTIVE:To describe the progression of HIV disease in a haemophilic cohort and to show the influence of treatment. DESIGN:11 year longitudinal clinical and laboratory study. SETTING:A haemophilia centre. PATIENTS:111 patients infected with HIV during October 1979 to July 1985. MAIN OUTCOME MEASURES:Symptoms of HI...

journal_title：BMJ (Clinical research ed.)

authors： Lee CA,Phillips AN,Elford J,Janossy G,Griffiths P,Kernoff P

更新日期：1991-11-02 00:00:00

abstract：OBJECTIVE:To examine the role of peak bone mass and subsequent postmenopausal bone loss in the development of osteoporosis and the reliability of identifying women at risk from one bone mass measurement and one biochemical assessment of the future bone loss. DESIGN:Population based study. SETTING:Outpatient clinic fo...

journal_title：BMJ (Clinical research ed.)

authors： Hansen MA,Overgaard K,Riis BJ,Christiansen C

更新日期：1991-10-19 00:00:00

abstract：OBJECTIVE:To assess general practitioners' decisions to request lumbar spine radiographs according to the guidelines of the Royal College of Radiologists. DESIGN:Prospective questionnaire survey of outpatients attending for lumbar spine radiography. SETTING:London community hospital. SUBJECTS:100 consecutive adult o...

journal_title：BMJ (Clinical research ed.)

authors： Halpin SF,Yeoman L,Dundas DD

更新日期：1991-10-05 00:00:00

abstract：OBJECTIVES:To determine whether fibrinogen and lipid concentrations are risk factors for ischaemic stroke. DESIGN:Case-control study with a population based comparison within the overall study. SETTING:Oxfordshire community stroke project and a neurology clinic. SUBJECTS:105 patients who had a transient ischaemic at...

journal_title：BMJ (Clinical research ed.)

authors： Qizilbash N,Jones L,Warlow C,Mann J

更新日期：1991-09-14 00:00:00

abstract：OBJECTIVE:To describe the mechanism established by Richmond, Twickenham, and Roehampton Health Authority to manage extracontractual referral requests made on behalf of its resident population and to examine its working in the first three months of the new arrangements. DESIGN:Description of the procedures for managing...

journal_title：BMJ (Clinical research ed.)

authors： Williamson JD

更新日期：1991-08-31 00:00:00

abstract：OBJECTIVE:To determine the effectiveness of oral rehydration in children with moderate dehydration caused by gastroenteritis, and to compare the complications of oral and intravenous treatment. DESIGN:Randomised controlled trial. SETTING:Emergency department and infectious diseases ward in a large urban teaching hosp...

journal_title：BMJ (Clinical research ed.)

authors： Mackenzie A,Barnes G

更新日期：1991-08-17 00:00:00

abstract：OBJECTIVE:To describe the association between epithelial cell IgM, which has previously been associated with an increased incidence of loss of renal graft in children, with a novel cutaneous eruption and unexplained native renal disease. DESIGN:Observational study on children with epithelial cell antibody presenting w...

journal_title：BMJ (Clinical research ed.)

authors： Deal JE,Groves RW,Harmer AW,Welsh KI,MacDonald DM,Rigden SP

更新日期：1991-07-20 00:00:00

abstract：OBJECTIVE:To obtain information about the computerisation of general practice in Wales, and to enable more effective planning of educational provision for doctors and other primary health care workers. DESIGN:Postal questionnaire sent to all general practices in Wales. SUBJECTS:553 general practices, of which 401 (73...

journal_title：BMJ (Clinical research ed.)

authors： Goves JR,Davies T,Reilly T

更新日期：1991-07-13 00:00:00

abstract：OBJECTIVE:To determine the relation between mothers' self reported drinking habits before, during, and after pregnancy and infants' mental and motor development at 18 months of age. DESIGN:Follow up study of all singleton live births born to primigravidas living in Dundee and booked into antenatal clinics from 1 May 1...

journal_title：BMJ (Clinical research ed.)

authors： Forrest F,Florey CD,Taylor D,McPherson F,Young JA

更新日期：1991-07-06 00:00:00

abstract：:In just 3 months in 1991, WHO increased its estimate of the number of people infected with HIV in all of Asia 2 fold (500,000-1 million). By 2000, WHO estimated that there will be 250,000 new cases each year in India and Thailand alone where HIV infection has spread most rapidly. A professor from the All India Insti...

journal_title：BMJ (Clinical research ed.)

authors： Tanne JH

更新日期：1991-06-29 00:00:00

abstract：OBJECTIVE:To appraise a new method of prenatal screening for Down's syndrome based on maternal serum concentrations of alpha fetoprotein, unconjugated oestriol, and human chorionic gonadotrophin combined with maternal age--the "triple test." DESIGN:Examination of the cost effectiveness of the triple test relative to s...

journal_title：BMJ (Clinical research ed.)

authors： Sheldon TA,Simpson J

更新日期：1991-05-11 00:00:00

abstract：OBJECTIVES:To examine how insurance companies assess proposals for life assurance from applicants with raised cholesterol concentrations and to determine the excess mortality rating applied. DESIGN:Survey of 49 companies underwriting term life assurance. SETTING:United Kingdom. SUBJECTS:Four fictional men aged 30 se...

journal_title：BMJ (Clinical research ed.)

authors： Neil HA,Mant D

更新日期：1991-04-13 00:00:00

abstract：:The opportunities for international public health collaboration through joint business ventures between the USSR and Western nations, an arrangement that would benefit the public, industry, and the medical community, are discussed. Evidence indicates that the state of health of the Soviet population is declining rapi...

journal_title：BMJ (Clinical research ed.)

authors： Gellert GA,Kaznady SI

更新日期：1991-03-16 00:00:00

abstract：OBJECTIVE:To assess the ability of radiographers to identify abnormal radiographs of patients attending accident and emergency departments. DESIGN:Prospective study over six weeks. SETTING:Teaching hospital casualty x ray department. PATIENTS:3394 consecutive patients referred for radiography. INTERVENTIONS:Radiogr...

journal_title：BMJ (Clinical research ed.)

authors： Renwick IG,Butt WP,Steele B

更新日期：1991-03-09 00:00:00

abstract：OBJECTIVE:To examine the extent to which changes in diagnostic methods and classification are responsible for the striking increase in incidence of primary liver cancer in Denmark since 1943. DESIGN:Analysis of the time trends in sex specific, age standardised incidence of primary liver cancer and unspecified liver ca...

journal_title：BMJ (Clinical research ed.)

authors： Anderson IB,Sørensen TI,Prener A

更新日期：1991-02-23 00:00:00

abstract：OBJECTIVE:To establish whether there is evidence of the efficacy of homoeopathy from controlled trials in humans. DESIGN:Criteria based meta-analysis. Assessment of the methodological quality of 107 controlled trials in 96 published reports found after an extensive search. Trials were scored using a list of predefined...

journal_title：BMJ (Clinical research ed.)

authors： Kleijnen J,Knipschild P,ter Riet G

更新日期：1991-02-09 00:00:00

abstract：OBJECTIVE:To determine whether in a patient with spontaneous pneumothorax the presence or absence of a pleural leak can be shown at the time of manual aspiration by use of a marker gas. Also, to find out if the technique can predict whether manual aspiration will be successful, hence avoiding the need for intercostal t...

journal_title：BMJ (Clinical research ed.)

authors： Seaton D,Yoganathan K,Coady T,Barker R

更新日期：1991-02-02 00:00:00

abstract：OBJECTIVE:To describe the characteristics of patients using non-orthodox health care and their pattern of use of conventional health care with respect to a particular problem. DESIGN:Postal survey of all 2152 practitioners of acupuncture, chiropractic, homeopathy, naturopathy, and osteopathy identified from 11 nationa...

journal_title：BMJ (Clinical research ed.)

authors： Thomas KJ,Carr J,Westlake L,Williams BT

更新日期：1991-01-26 00:00:00

abstract：OBJECTIVE:To determine the prevalence of sexually transmitted diseases in patients with normal and abnormal cervical smears. DESIGN:A prospective study of asymptomatic women with normal cervical smears attending their general practitioner and newly referred patients with abnormal smears attending a colposcopy clinic. ...

journal_title：BMJ (Clinical research ed.)

authors： Smith JR,Murdoch J,Carrington D,Frew CE,Dougall AJ,MacKinnon H,Baillie D,Byford DM,Forrest CA,Davis JA

更新日期：1991-01-12 00:00:00

abstract：OBJECTIVES:To examine trends over time in the rates of admission to hospital for accidents of preschool children and to study patterns of repeated admissions for accidents in these children. DESIGN:Analysis of linked, routine abstracts of hospital inpatient records for accidents. SETTING:Six districts in the Oxford R...

journal_title：BMJ (Clinical research ed.)

authors： Sellar C,Ferguson JA,Goldacre MJ

更新日期：1991-01-05 00:00:00

abstract：OBJECTIVE:To determine whether inhaled salmeterol, a new long acting inhaled beta adrenergic agonist, reduces nocturnal bronchoconstriction and improves sleep quality in patients with nocturnal asthma. DESIGN:Randomised, double blind, placebo controlled crossover study. SETTING:Hospital outpatient clinics in Edinburg...

journal_title：BMJ (Clinical research ed.)

authors： Fitzpatrick MF,Mackay T,Driver H,Douglas NJ

更新日期：1990-12-15 00:00:00

abstract：OBJECTIVES:To determine the prevalence and associations of symptoms of fatigue. DESIGN:Questionnaire survey. SETTING:London general practice. PARTICIPANTS:611 General practice attenders. MAIN OUTCOME MEASURES:Scores on a fatigue questionnaire and reasons given for fatigue. RESULTS:10.2% Of men (17/167) and 10.6% o...

journal_title：BMJ (Clinical research ed.)

authors： David A,Pelosi A,McDonald E,Stephens D,Ledger D,Rathbone R,Mann A

更新日期：1990-11-24 00:00:00

abstract：OBJECTIVE:To compare ultrasonography with intravenous urography in the investigation of adults with haematuria. DESIGN:Prospective study entailing the examination of all patients with both investigations concurrently. The investigations were performed independently on routine lists by different duty radiologists. Each...

journal_title：BMJ (Clinical research ed.)

authors： Spencer J,Lindsell D,Mastorakou I

更新日期：1990-11-10 00:00:00

abstract：OBJECTIVE:To investigate the effect of overweight on premature mortality and work disability in young and middle aged Finns. DESIGN:Prospective cohort study based on data collected in the multiphasic health examinations by the Social Insurance Institution of Finland from 1966 to 1972 and follow up until 1982. SETTING...

journal_title：BMJ (Clinical research ed.)

authors： Rissanen A,Heliövaara M,Knekt P,Reunanen A,Aromaa A,Maatela J

更新日期：1990-10-13 00:00:00

abstract：OBJECTIVES:To investigate current practice of screening children from abroad for infections after coming to the United Kingdom, and to make recommendations for future practice. DESIGN:A review of literature and a questionnaire sent to all health authorities and boards in the United Kingdom. SETTING:All health authori...

journal_title：BMJ (Clinical research ed.)

authors： Shabde N,Waterston T

更新日期：1990-10-06 00:00:00

abstract：OBJECTIVE:To investigate the results of resuscitation of patients with cardiac arrest by ambulance staff with extended training in West Yorkshire. DESIGN:Study of all such attempts at resuscitation over 32 months, based on the standard report form for each call made by the ambulance staff and the electrocardiogram tha...

journal_title：BMJ (Clinical research ed.)

authors： Wright D,Bannister J,Ryder M,Mackintosh AF

更新日期：1990-09-22 00:00:00

abstract：OBJECTIVES:To determine whether measurement of total cholesterol concentration is sufficient to identify most patients at lipoprotein mediated risk of coronary heart disease without measurement of triglyceride and high density lipoprotein (HDL) cholesterol concentrations. DESIGN:Cross sectional screening programme. S...

journal_title：BMJ (Clinical research ed.)

authors： Neil HA,Mant D,Jones L,Morgan B,Mann JI

更新日期：1990-09-22 00:00:00

abstract：OBJECTIVE:To study delays between sending referral letters and the outpatient appointment and to assess the content of referral and reply letters, their educational value, and the extent to which questions asked are answered by reply letters. DESIGN:Retrospective review of referrals to 16 consultant orthopaedic surgeo...

journal_title：BMJ (Clinical research ed.)

authors： Jacobs LG,Pringle MA

更新日期：1990-09-08 00:00:00

abstract：OBJECTIVE:To determine the prevalence of asthma in cohorts of Finnish young men in the period 1926-89. DESIGN:A retrospective analysis using reports and statistics of Finnish defence forces. SETTING:Call up examinations of candidates for military conscription and examination of conscripts discharged because of poor h...

journal_title：BMJ (Clinical research ed.)

authors： Haahtela T,Lindholm H,Björkstén F,Koskenvuo K,Laitinen LA

更新日期：1990-08-04 00:00:00

abstract：OBJECTIVE:To examine the patterns of physical activity among British schoolchildren aged 11 to 16 and to assess whether the children experience the intensity and duration of physical activity that are believed to stress the cardiopulmonary system appropriately. DESIGN:Cross sectional study of a sample of children draw...

journal_title：BMJ (Clinical research ed.)

authors： Armstrong N,Balding J,Gentle P,Kirby B

更新日期：1990-07-28 00:00:00

abstract：OBJECTIVE:To compare the prevalence of silent myocardial ischaemia associated with coronary artery disease in diabetic subjects with that in controls of similar age and sex. DESIGN:A controlled study in which subjects with positive findings on exercise electrocardiography, 24 hour electrocardiographic recording, or dy...

journal_title：BMJ (Clinical research ed.)

authors： Koistinen MJ

更新日期：1990-07-14 00:00:00

abstract：OBJECTIVE:To evaluate the outcome of liver transplantation in patients with alcoholic cirrhosis with respect to selection criteria, survival, and evidence suggesting a return to harmful drinking. DESIGN:Nine year retrospective study. SETTING:Cambridge and King's College Hospital liver transplant programme. SUBJECTS:...

journal_title：BMJ (Clinical research ed.)

authors： Bird GL,O'Grady JG,Harvey FA,Calne RY,Williams R

更新日期：1990-07-07 00:00:00

abstract：OBJECTIVE:To explore genetic and environmental contributions to the influence of parental social class and region of upbringing on adult human fatness. DESIGN:Survey of sample of adults who had been adopted in childhood to relate their body mass index to sociodemographic variables in a series of multiple linear regres...

journal_title：BMJ (Clinical research ed.)

authors： Teasdale TW,Sørensen TI,Stunkard AJ

更新日期：1990-06-23 00:00:00